Active dendrites and spike propagation in multicompartment models of oriens‐lacunosum/moleculare hippocampal interneurons
نویسندگان
چکیده
منابع مشابه
Active dendrites regulate spectral selectivity in location-dependent spike initiation dynamics of hippocampal model neurons.
How does the presence of plastic active dendrites in a pyramidal neuron alter its spike initiation dynamics? To answer this question, we measured the spike-triggered average (STA) from experimentally constrained, conductance-based hippocampal neuronal models of various morphological complexities. We transformed the STA computed from these models to the spectral and the spectrotemporal domains a...
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Computational analyses of dendritic computations often assume stationary inputs to neurons, ignoring the pulsatile nature of spike-based communication between neurons and the moment-to-moment fluctuations caused by such spiking inputs. Conversely, circuit computations with spiking neurons are usually formalized without regard to the rich nonlinear nature of dendritic processing. Here we address...
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Richard Naud, Brice Bathellier and Wulfram Gerstner 1 Department of Physics, University of Ottawa, 150 Louis Pasteur, ON, K1N 6N5, Canada. 2 Unit of Neuroscience Information and Complexity (UNIC) CNRS UPR-3239, 1 av. de la Terasse, Gif-sur-Yvette, 91198, France. 3 School of Computer and Communication Sciences and School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Building AAB La...
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A complete single-neuron model must correctly reproduce the firing of spikes and bursts. We present a study of a simplified model of deep pyramidal cells of the cortex with active dendrites. We hypothesized that we can model the soma and its apical dendrite with only two compartments, without significant loss in the accuracy of spike-timing predictions. The model is based on experimentally meas...
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1. Intracellular recordings, in conjunction with fura-2 fluorescence imaging, were used to evaluate the contribution of the different Ca2+ channel subtypes to the Ca2+ influx induced by back-propagating trains of action potentials. High-threshold channels contributed mainly to Ca2+ influx in pyramidal cell somata and proximal dendrites, whereas low-threshold and other Ni(2+)-sensitive channels ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2003
ISSN: 0022-3751,1469-7793
DOI: 10.1113/jphysiol.2003.046177